35+ clinical studies. Definitive science.

Our peer-reviewed, published scientific studies have expanded our NAD+ knowledge and validated our approach. Each clinical trial adds to the growing body of evidence supporting Niagen's efficacy. We pursue scientific excellence without compromise.

Backed by gold standard science, quality, and safety

Efficacy backed by peer-reviewed published research

Niagen® is supported by 35+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 65% of registered ongoing or completed nicotinamide riboside trials use Niagen.²

Partnership with 200+ institutions: Our CERP program partners with top institutions like Mayo Clinic, National Institute on Aging, Harvard, and Cambridge.

Backed by independent research: Over 90% of Niagen studies are investigator-driven and third-party funded.

View studies and publications

Published in Nature Communications 2016

Trammell et al., 2016.

Published in The American Journal of Clinical Nutrition in 2017

Airhart et al., 2017.

Published in Nature Communications in 2018

Martens et al., 2018.

Published in The American Journal of Clinical Nutrition in 2018

Dollerup et al., 2018.

Published in Nature Communications in 2019

Conze et al., 2019.

Published in Scientific Reports in 2019

Dollerup et al., 2019.

Published in The American Journal of Clinical Nutrition in 2019

Elhassan et al., 2019.

Published in The Journal of Physiology in 2019

Dollerup et al., 2019.

Published in The American Journal of Clinical Nutrition in 2020

Remie et al., 2020.

Published in Molecular Systems Biology in 2020

Zhang et al., 2020

Published in The Journal of Clinical Investigation in 2020

Zhou et al., 2020

Published in Metabolites in 2020.

Tinnevelt et al., 2020

Published in the The Journal of Clinical Endocrinology & Metabolism in 2021.

Nascimento et al., 2021

Published in Theranostics in 2021

Li et al., 2021

Published in Advanced Science in 2021

Altay et al., 2021

Published in The Journal of Physiology in 2021

Stocks et al., 2021.

Published in Movement Disorders in 2021

Veenhuis et al., 2021

Published in Molecular Systems Biology in 2021

Zeybel et al., 2021

Published in the Journal of Clinical Investigations in 2022

Wu et al., 2022

Published in Cell Metabolism in 2022

Brakedal et al., 2022

Published in JACC in 2022

Wang et al., 2022

Published in Aging Cell in 2022

Vreones et al., 2022

Published in Science Advances in 2023

Lapatto et al., 2023.

Published in Translational Neurodegeneration in 2023

Yulug et al., 2023

Published in iScience in 2023

Gaare et al., 2023

Published in npj Aging

Peluso et al., 2023

Published in JCI Insight in 2023

Ahmadi et al., 2023

Published in Cell Reports Medicine in 2023

Han et al., 2023

Published in Movements Disorders Journal in 2023

Presterud et al., 2023

Published in GeroScience in 2023

Orr et al., 2023

Published in Nature Communications in 2023

Berven et al., 2023

Published in Cells in 2023

Wu et al., 2024

Published in Nature Communications in 2024

McDermott et al., 2024

Published in the journal of Magnetic Resonance in Medicine in 2024

Nanga et al., 2024.

Published in Pediatric Blood & Cancer in 2024

Bhandari et al., 2024

Published in Brain Communications in 2024

Yulug et al., 2025

Published in Alzheimer’s and Dementia Journal in 2025

Wu et al., 2025

Published in the Clinical Journal of the American Society of Nephrology in 2025

Ahmadi et al., 2025

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